Benzaldehyde dehydrogenase (NADP+)
| benzaldehyde dehydrogenase (NADP+) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| EC number | 1.2.1.7 | ||||||
| CAS number | 9028-89-1 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a benzaldehyde dehydrogenase (NADP+) (EC 1.2.1.7) is an enzyme that catalyzes the chemical reaction
- benzaldehyde + NADP+ + H2O
benzoate + NADPH + 2 H+
The 3 substrates of this enzyme are benzaldehyde, NADP+, and H2O, whereas its 3 products are benzoate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NADP+ oxidoreductase. Other names in common use include NADP+-linked benzaldehyde dehydrogenase, and benzaldehyde dehydrogenase (NADP+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation.
References
- GUNSALUS CF, STANIER RY, Gunsalus IC (1953). "THE ENZYMATIC CONVERSION OF MANDELIC ACID TO BENZOIC ACID III. : Fractionation and Properties of the Soluble Enzymes". J. Bacteriol. 66 (5): 548–53. PMC 317432. PMID 13108854. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=317432.
- Stachow CS, Stevenson IL, Day D (1967). "Purification and properties of nicotinamide adenine dinucleotide phosphate-specific benzaldehyde dehydrogenase from Pseudomonas". J. Biol. Chem. 242 (22): 5294–300. PMID 4383635.